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AtomiMed: Hierarchical Atomic Fact-Checking for Universal Clinical-Aware Medical Report Evaluation

Yuan Wang, Wanxing Chang, Songtao Jiang, Shujian Gao, Xiaotian Zhang, Ruifeng Yuan, Weiwei Cao, Bowen Shi, Ling Zhang, Zuozhu Liu, Jianpeng Zhang

arXiv:2606.31292v1cs.CE

TL;DR

Reliable evaluation of medical reports remains a challenge because existing metrics have limitations in clinical factuality and modality generality. AtomiMed decomposes reports into hierarchical clinical facts and cross-verifies them, achieving significantly higher correlation with radiologist judgment than prior metrics across four reader-study benchmarks.

  • Problem

    Reliable medical report evaluation remains insufficiently studied, and existing metrics do not jointly provide modality generality, fine-grained attribution, and clinical factual assessment.

    Source: §1 · p. 2
  • Method

    AtomiMed decomposes reports into Disease- and Attribute-level Atomic Clinical Facts and bidirectionally cross-verifies reports to assess diagnostic detection and descriptive accuracy.

    Source: §1 · p. 2
  • Results

    Across four reader-study benchmarks, AtomiMed achieves significantly higher correlation with radiologist judgment than all prior metrics, including GREEN.

    Source: §1 · p. 2
  • Takeaways & Limitations

    Its audit traces expose systematic attribute- and disease-level deficiencies invisible to prior metrics.

    Source: §1 · p. 3

    The authors identify future work in reducing inference cost, extending attributes to longitudinal imaging comparisons, and broadening benchmark coverage to additional specialties.

    Source: §4 · p. 9

Abstract

from arXiv · show

Traditional metrics for Medical Report Generation (MRG) predominantly rely on surface-level n-gram overlap, which fails to capture clinical factual accuracy and often overlooks catastrophic diagnostic errors. We address this fundamental limitation by proposing \textbf{AtomiMed}, a universal, modality-agnostic evaluation framework that decomposes complex medical narratives into a standardized, multi-level hierarchy of Atomic Clinical Facts, encompassing Disease-level entities and Attribute-level descriptors, including location, morphology, and severity. By implementing an Agentic Cross-Verification loop between ground-truth and predicted reports, AtomiMed simulates a multi-radiologist peer-review process to verify clinical consistency, thus enabling the decoupled assessment of diagnostic detection and descriptive accuracy. To facilitate standardized evaluation, we introduce \textbf{MRGEvalKit}, an open-source toolkit for automated hierarchical extraction, and curate \textbf{OmniMRG-Bench}, a comprehensive multi-modal benchmark covering X-ray, CT, MRI, and Ultrasound. Extensive experiments on multiple expert-annotated reader studies demonstrate that AtomiMed achieves significantly higher correlation with human radiologist judgment compared to traditional and model-based metrics. Our code are release at https://github.com/Venn2336/MRGEvalkit

1 Introduction

AtomiMed addresses the challenge of evaluating clinically grounded medical reports by decomposing them into hierarchical Atomic Clinical Facts and bidirectionally cross-verifying reports. It supports modality-agnostic assessment and interpretable per-finding error attribution.

1 Introduction

  • Clinically critical misses such as omitted pneumothorax or reversed laterality can create false confidence and risk patient safety; evaluation must be factually grounded, structure-aware, and robust across imaging modalities.Source: §1 · p. 2
  • Lexical metrics miss semantic reversals (BLEU, ROUGE, METEOR); structure-based metrics lack modality breadth, while GREEN lacks per-finding audit traces and incurs substantial inference costs.No existing metric simultaneously provides modality universality, fine-grained attribute correctness, and interpretable error attribution.Source: §1 · p. 2
  • AtomiMed decomposes reports into Disease-level and Attribute-level Atomic Clinical Facts, then bidirectionally cross-verifies reports to separately assess diagnostic detection and descriptive accuracy with question-level audit traces.It computes precision, recall, and F1 at both hierarchy levels.Source: §1 · pp. 2–3
  • Across four radiologist-annotated benchmarks, AtomiMed achieves significantly higher correlation with radiologist judgment than prior metrics, including GREEN, while exposing granular per-finding errors.The experiments cover multiple modalities and report systematic disease- and attribute-level deficiencies invisible to prior metrics.Source: §1 · pp. 2–3
  • OmniMRG-Bench spans X-ray, CT, MRI, and Ultrasound with standardized expert radiologist annotations, alongside MRGEvalKit, an open-source toolkit for reproducible hierarchical atomic scoring.Source: §1 · p. 3

2 Method

AtomiMed converts reports into hierarchical atomic clinical facts and uses bidirectional evidence-based verification to assess disease detection and attribute accuracy. OmniMRG-Bench supports evaluation across four imaging modalities with radiologist-verified annotations.

2.1 Atomic Decomposition

  • AtomiMed prompts an instruction-tuned LLM to extract binary disease-level findings and location, size, morphology, severity, quantity, and temporal-change attributes as structured atomic facts.A fixed prompt template and robust parser constrain the model to emit valid JSON.Source: §2.1 · pp. 3–4

2.2 Agentic Cross-Validated Assessment

  • A bidirectional cross-verification loop asks ground-truth and generated-report disease questions against each other, then scores attributes only for findings aligned in both directions.Disease names are matched to attribute keys using fuzzy string similarity (θ = 0.8); when both reports contain no disease statements, scores are set to 1.Source: §2.2 · pp. 4–5, Figure 1 · p. 4
  • Equal-weight aggregation separates diagnostic detection from descriptive accuracy, with each score traceable to a mismatched question for interpretable error attribution.Source: §2.2 · p. 5

2.3 OmniMRG-Bench

  • OmniMRG-Bench spans X-ray, CT, MRI, and Ultrasound across 9 anatomical systems and 6 attribute categories, with over 178K radiologist-verified hierarchical QA pairs.Its attribute pairs are dominated by location (∼62.9K) and size (∼31.5K) descriptors; reports come from public datasets and de-identified clinical archives.Source: Figure 2 · p. 5, §2.3 · p. 5

3 Experiments and Results · 3.1 Experiment Settings

The experiments evaluate AtomiMed using two complementary paradigms.

3.1 Experiment Settings

  • AtomiMed is evaluated across two complementary experimental paradigms.The supplied passage does not specify the paradigms or complete the purpose of the evaluation.Source: §3.1 · p. 5

Evaluation Benchmarks and Paradigms.

The evaluation uses expert-annotated benchmarks to assess metric alignment with radiologist error counts and a cross-modal pairwise paradigm to compare model preferences with human expert judgment.

Evaluation Benchmarks and Paradigms.

  • Four expert-annotated benchmarks—ReXVal, ReFiSco-v0, RadEvalX, and RaTE-Eval—support metric–radiologist error-count correlation evaluation.They provide radiologist error counts, line-level severity annotations, or typed error annotations; RaTE-Eval is derived from MIMIC-IV and Radiopaedia.Source: Evaluation Benchmarks and Paradigms · p. 6, Table 2 · p. 6
  • The dimensionless pairwise paradigm compares 10 state-of-the-art models on 20 cases each across X-ray, CT, MRI, and ultrasound against human expert judgment.Each case produces a 10×10 model-comparison matrix for validation against human judgment.Source: Evaluation Benchmarks and Paradigms · p. 6

Baselines. · Implementation and Evaluation Protocol.

AtomiMed is evaluated against lexical, embedding-based, medical-specialized, and LLM-as-a-Judge metrics under deterministic implementation settings, with separate correlation and human-preference protocols.

Baselines.

  • The baseline suite includes lexical metrics BLEU-1/4, ROUGE-L, METEOR, and CIDEr for n-gram overlap.Source: Baselines · p. 6
  • BERTScore serves as the embedding-based baseline for semantic similarity via contextual embeddings.Source: Baselines · p. 6
  • Medical-specialized baselines are F1 RadGraph [6], SembScore, and graph-based RaTEScore.Source: Baselines · p. 6
  • GREEN is the LLM-as-a-Judge baseline for holistic clinical validation.Source: Baselines · p. 6

Implementation and Evaluation Protocol.

3.2 Main Results · Correlation with Radiologist Judgments.

AtomiMed aligns closely with radiologist judgments, with its strongest stated advantage being interpretable, finding-level audit traces on RaTE-Eval.

Correlation with Radiologist Judgments.

  • 0.806 Spearman’s ρ on ReXVal exceeds GREEN’s 0.798 and traditional NLP metrics, supporting AtomiMed’s strong alignment with expert clinical judgment.The passage attributes this alignment to detection of errors radiologists penalize, including omissions and laterality shifts.Source: Correlation with Radiologist Judgments · p. 7
  • On RaTE-Eval, AtomiMed maintains comparable performance while providing fine-grained, interpretable audit traces for each clinical finding, unlike holistic LLM judges.Table 3’s stated scope is dimensionless pairwise-preference consistency across imaging modalities, measured with MAE, Acc, and Kendall’s τ against standard NLP and specialized medical metrics.Source: Correlation with Radiologist Judgments · p. 7, Table 3 · p. 7

Pairwise Preference and Clinical Awareness.

AtomiMed more closely emulates radiologist preferences than the reported baselines on X-ray and maintains meaningful correlation across modalities. GREEN’s correlation degrades on cross-sectional imaging.

Pairwise Preference and Clinical Awareness.

  • 95.71% ACC and τ = 0.9807 on X-ray, with MAE 0.0214, distinguish AtomiMed from GREEN (MAE 0.1857, ACC 63.57%) and lexical baselines (13%–21% ACC).The passage describes AtomiMed’s MAE as an order of magnitude lower than GREEN’s and over twenty times lower than any lexical baseline.Source: Pairwise Preference and Clinical… · p. 7
  • 84.33% ACC on CT and 49.86% on Ultrasound show AtomiMed’s cross-modal performance; GREEN reaches 33.83% on CT and RaTEScore 35.00% on Ultrasound.GREEN’s Kendall’s τ falls from 0.6481 on X-ray to 0.3283 on CT and 0.1513 on MRI.Source: Pairwise Preference and Clinical… · p. 8
  • In MRI, AtomiMed’s scores cluster around the regression line (τ = 0.42, MAE = 0.281), unlike GREEN’s wide scatter (τ = 0.18, MAE = 0.379).The passage characterizes GREEN’s MRI agreement as near-random.Source: Pairwise Preference and Clinical… · p. 8, Figure 3 · p. 8

Granular Performance Analysis via AtomiMed.

AtomiMed’s granular analysis exposes systematic, non-uniform failures hidden by holistic scalar metrics. Models perform better on Morphology than on Severity and Size, while disease-level scores vary sharply across systems and models.

Attribute-level analysis

  • Morphology scores are 6.0–13.2 across models, versus 1.3–5.9 on Severity and 1.0–6.9 on Size, revealing weak quantification of clinical significance and extent.HuatuoGPT-34B scores 1.27 and Qwen2.5-VL-7B scores 0.80 on Severity, near the floor.Source: Granular Performance Analysis via… · p. 8

Disease-level analysis

  • Respiratory scores reach 21.84 for HuluMed-7B, while Digestive scores are 0.32–10.93, Reproductive 1.31–5.34, and Urinary 0.07–6.91.The passage describes respiratory dominance and the other systems as severely underserved, consistent with chest-centric pretraining biases.Source: Granular Performance Analysis via… · p. 8
  • InternVL3.5-38B scores 26.20 on Endocrine but 0.97 on Urinary, exemplifying uneven anatomical coverage invisible to prior evaluation metrics.AtomiMed identifies these fine-grained deficiencies through its granular analysis.Source: Granular Performance Analysis via… · p. 8

4 Conclusion

AtomiMed is a modality-agnostic framework for medical report generation evaluation that decomposes reports into Disease- and Attribute-level Atomic Clinical Facts and uses bidirectional Agentic Cross-Verification to computationally operationalize radiological peer review.

  • AtomiMed decomposes reports into Disease- and Attribute-level Atomic Clinical Facts and applies bidirectional Agentic Cross-Verification as a computational protocol for radiological peer review.Source: §4 · p. 8
  • Figure 4 presents category-level medical-attribute and disease-level anatomical-system performance heatmaps, where higher scores indicate better alignment with human-verified atomic facts.Source: Figure 4 · p. 9
  • Future work will develop distilled backbones to reduce inference cost, extend the attribute hierarchy to longitudinal imaging, and broaden benchmark coverage to more clinical specialties.Source: §4 · p. 9
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